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File Version :
Description : USB Serial Port Driver
Copyright : Copyright (c) Standard Microsystems. 2000
Product Version : 1.30
Product Name : Standard Microsystems Windows 2000 USB Serial Port Driver
Company Name : Standard Microsystems
Internal Name : smscser.sys
File Size: 63076 byte(s) 61.612 KB
MD5 : c76550bb24e6d26e88f5e3bd67b5b0d5
SHA1: 488855BE8FFF8EB456DFBFA076148968A40A8BDB

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How to Install SMCISA.SYS
Repair Sys ProblemsFixing a corrupted or missing SMCISA.SYS error is an easy process with a few steps. Open the zip-file you downloaded.Extract the .sys file to a location on your computer. We recommend you to unzip the file to the directory of the program that is requesting the file.
If that doesn't work, you will have to extract the file to your system directory.
By default, this is C:/WINNT/system32/drivers (Windows NT/2000).
or C:/Windows/system32/drivers (Windows XP, Vista, 7).
Make sure overwrite any existing files (but make a backup copy of the original file)
That should be it. Although not necessary you can reboot your computer as well.